If protein is lacked in a diet a person develops kwashiorkor which is caused when high levels of carbohydrates are eaten to overcome the lack of protein in the diet. One symptom of kwashiorkor is the abnormal collection of fluid around the abdomen due to the lack of protein in the blood. The body cannot retain water by osmosis and fluid accumulates in tissues causing them to become waterlogged.
Vitamin Categories
Vitamins cannot be synthesized by the body so must be supplied by diet. Vitamins have no common structure or function but are essential in small amounts for the body to be able to utilize other dietary components efficiently.
Vitamins fall into two categories, fat soluble vitamins such as vitamin A, D, E and K which are ingested with fatty foods and water soluble vitamins such as the B group vitamins and vitamin C. Vitamins are known as micronutrients because only small quantities are required for a healthy diet, in fact fat soluble vitamins can be toxic in high concentrations, for example the body stores vitamin A, or retinol, in the liver as it is toxic if kept in high concentrations in the blood stream, a dose of more than 3300mg of vitamin A can be considered toxic. Water soluble vitamins such as vitamin C and B groups vitamins can be excreted in the urine if in excess in the diet.
Vitamins A
Vitamin A is essential to the proper functioning of the retina in the eye and the epithelial tissues. A lack of vitamin A results in dry, rough skin, inflammation of the eyes, a drying or scarring of the cornea - xerophthalmia, which occurs when the secretion of lubricating tears is stopped, the eyelids become swollen and sticky with pus. Mucous surfaces of the eye may become eroded allowing infection to set in, leading to ulceration and destruction of the cornea. Night blindness - an inability to see in dim light can also occur. Rod cells in the retina of the eye detect light of low intensity, they convert vitamin A into a pigment, rhodopsin, which is bleached when light enters the eye. Rod cells resynthesis rhodopsin, but if there is a deficiency of the vitamin, rod cells can no longer function and the result is night blindness. Epithelial cells use retinol to make retinoic acid, an intracellular messenger used in cell differentiation and growth. Without retinoic acid epithelial cells are not maintained properly and the body becomes susceptible to infections, particularly measles and infections of the respiratory system and gut.
Xenophthalmia is common among children who's diets consist of mainly cereals with little meat or fresh vegetables, this is common in Indonesia, Bangladesh, India and the Philippines.
Vitamins D
Vitamin D, or calciferol, is another fat soluble steroid vitamin which functions to stimulate calcium uptake from the gut and its deposition in bone. vitamin D acts as a hormone when converted by enzymes in the gut and liver into an active form of "active vitamin D", which stimulates epithelial cells in the intestine to absorb calcium. vitamin D is therefore essential in growing children's diets to enable the growth of strong bones. Without adequate amounts of vitamin D children can develop rickets, which is the deformation of the legs caused when they lack calcium to strengthen the bones. In adults a lack of vitamin D in the diet can lead to osteomalacia, a progressive softening of the bones which can make them highly susceptible to fracture. |
